New Ideas in Chelation Therapy
نویسنده
چکیده
The cornerstone of the treatment of Wilson’s disease is a reduction of copper levels in vivo using the orallyadministered chelating agents D-penicillamine and trientine dihydrochloride. Patients with side-effects from receiving multiple blood transfusions for the amelioration of inherited anaemias are also successfully treated with chelating agents. Blood transfusion elevates these patients’ iron concentrations, which, if not reduced by chelation, will damage vital organs. In recent years the deleterious role of metal ions in neurological diseases has come under the spotlight. In particular, some investigators believe that iron, copper and zinc have a role in the progression of Alzheimer’s disease (AD) and that chelating agents could mitigate the disease.
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